The Cincinnati Bengals are set to face the Detroit Lions on Sunday, October 5, 2025, at Paycor Stadium in Cincinnati, OH. Here are some key details about the matchup¹:

– *Game Details:*
– *Date:* October 5, 2025
– *Time:* 4:25 PM ET (21:25 WAT)
– *Venue:* Paycor Stadium, Cincinnati, OH
*Predictions and Odds:*
– The Lions are favored to win, with a 56% chance of victory, according to simulations by Dimers and Stats Insider.
– The predicted final score is Lions 25, Bengals 24.
– The Bengals are listed as 1.5 to 8.5-point underdogs, depending on the source, with odds of $4.25 to $1.24 on the moneyline.² ³
*Injury Update:*
– Detroit Lions cornerback D.J. Reed is expected to miss the game due to a hamstring injury sustained during their Week 4 win against the Cleveland Browns.⁴
*Team History:*
– The Bengals have a seven-game winning streak against the Lions and are 10-3 overall in their head-to-head matchups.⁵